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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22e300938044e43fb5a6972995b2e426ba9ad6bf1680f1318bfaf25361b9eec' 
  AND token = '6OaIAOaGQg+vl+Kivk3cN9t3LvQyUiHuvqNOngl6CeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}