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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd55741cdbf0bb0856689d1b3d518d68296434098f7487a9a1b9162566f3d96' 
  AND token = 'CMo/lGedqm1rtB8NVmuE33qqdHpW9laCIySEOgDxEdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}