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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7b5a0c36be6cacc17820d8a492695cedaef1a1468055dfa2ef445954864f606' 
  AND token = 'GA1ynlj+ShKPFSa/T/z/l+qDwDjjU14K1FXqdq3amCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}