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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d35998c0474826f7d2c7bcb2f6044a70e9cfa0c2c9a4540d444c676c9c7f80a' 
  AND token = 'RCCqTop8VHXjLSf27MtvXaHl5bX2FxrExkAjLfeiUs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}