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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0454a88022f1af804805d1b4117f07ebb707c3dde7871c5ac19222cbb8425b51' 
  AND token = 'qLLlBLng409ZpHJylnd1B7OmISvCXH9fso7UnOg+pY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}