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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e4065dd584cdf67c8ccd56512dd5d17f0a32ff18fe03daac433a657485bf14' 
  AND token = 'yS8qo6TB0InbEqPF9LzTFZrPDhtA7EFn0RNa9rh83aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}