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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8268ad3cef5ed43a7e10d35f227ad526734a19043c271e2e0216993f72b3f6f7' 
  AND token = 'WAtSyeoTQYoI2k8KxwW/vkZQVmmVGc5UE1Q7Q4eWM6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}