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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3153a88fa74f59f015514ab899fe882e7439b5afcfb8a6a06ffb47c6de2be705' 
  AND token = '+6H1oSjV6DOt2xyeiv1xZAY9U07GItVI/iwexlQ6zNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}