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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc082a28718d0e32ebe0d534139766e558877cb6f0f70f411ff4ed706fd40c2' 
  AND token = 'JYpT6Zq4c/lUfhUhFvbm7z+TPjkZnnyaLNk43x9JN50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}