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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0449cb5d9ae720167298cacf096d10eec5dfa21038f9f64e3b084d614eaa31' 
  AND token = '5yOaORPsE9Yx2q3rmGVR+4mbFGTdkYLyVwFxWmw5JXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}