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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8737d888c3a340afd6d6f161ed519cd40581b38e2f0466d6e44f80c8e8f87944' 
  AND token = 'DUEAgBuqK8teza0NjJG0sRt0LsozlsA9ASd8wtaOqXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}