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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2d328964d606e9cf15e62022cd0845247f6a0cccad9168f7439d425c6255685' 
  AND token = '4XmEA0Fxnf45KwbTiLS45iKDFGNvGwkwsqfMdvFQLe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}