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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ecd14cb225b12e08715bffa14ce38bc0c5265d0b8bf8926d19a327e3db3d22' 
  AND token = '2zo8avoxioOCi4iDdZTrUTRcMhi8qyJF1seR3AfclhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}