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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14e0c8e6362a5ce89fd3db52fbc5cfbbe3bafd769cd2ef6717e97326aeb061da' 
  AND token = 'p3tyWJOO+8zRheyuAh9kYlSDlF4nLvdsPoLwZapU73o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}