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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6457c28508cac2fd47a16aa6f45b3355837e0409eb7b17b827288f949e0e134a' 
  AND token = '0GyADY5tLQKK6DS5DyC8cNJEAFq3y3aG/dIkFYAyzUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}