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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a0d7d540624e8c29b03d709a1adc782955c8b89d0beea3e8c355b60de1cb40' 
  AND token = 'e7c3/eQSzcf/atNWiPtDtqlH4FaO0f4b1LsuFpVelUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}