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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60a956cc16a3c180c9f9dbc395e2fbc1d60a96f09e24ce1084a60256b0896877' 
  AND token = 'wmZOoBisBOr0Pht0Z1mpzcStZeYhnmG//ZKkxfW1YKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}