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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7d6781c1a1d08ac74797266d5a0bf2bc3b353159cb12085e1cc45de74d0f0d3' 
  AND token = 'EFq1G0dRykCVBorgtzAcAQMZi4QiNtZ2aSTKFCZz/xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}