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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d21407e152921806c586ac911b67cb060a8fb32a07b7af0e9fa15457078b6c' 
  AND token = 'nXPjJyqyMLH5QcLdFPZ9cMzY/MyjdndNFReT/lxmLqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}