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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8240f440129c1769d8195141b2121532b50b5c6aa8ee7175e457f94b7bad7ed2' 
  AND token = 'TCL7crN0UTsZL5W+KrmrYvdju4hcFSJu9Ajkz1eZR74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}