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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6df18027ac26736f1af0a05adf5f639dc18f93eb4cd886f0bf9ea6ba3541acdb' 
  AND token = 'EeEpzK0HPHZ7EKcCSLZMQ6AjVRUhg7gzPsXztDrgFdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}