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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ffa3706d3e6dd8dce40a53269134ffb45e4287b2a81323b5e12d99a6f4e4842' 
  AND token = 'sc6S+VDUsUCzRT7rhzj7hOlolAVPcehCPs/JhSkeuBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}