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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af541567fae40e21f330e014a5d10678aeeb2a61b2f15a9a2039a8e15faf1a77' 
  AND token = '1QKBrr8AmNIWonzckT6ZR2qC7Nt3ms8LhcA4QqO8lqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}