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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86490495835728974f202c734bab2c2111aba68d8aa1c56d97b279471e8a0f50' 
  AND token = 'NSi1e6/ZXTgJ8rzaLsEk9cG4BcHeHZ3cdsm3twUp888=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}