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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14b649633f43d0ccb7d35689ad1266ca570dde2a0b56632b6492928011226416' 
  AND token = 'qaQrbyoyAY7i0j0DH9pIqLi3J3t6vfqdpYr5YIwI+Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}