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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0723cedbfee7aca64c1b9b44661ecca38fdf3428d4f9c06dfb9e43c382441971' 
  AND token = 'aa24a0mImSB8VtcoB0GwQs08vdZEkPFLKCUfOvaT8Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}