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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741caefd9a4bd3d51eaa327caea0538d55e694a81eb1f9ad70ec51b4d8b263dd' 
  AND token = 'V4s7MeOZOK4W7zZMebpmUpKmkN3tsWDS/jGOV822LZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}