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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10ba8734d1a364c33a7b36bd29903f6deec07a9a3e88d26b9698da9d443234d6' 
  AND token = 'Zc6FKTHXYaBf/ayD6HuKhJxAZapc25yRwbXHT/FuWb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}