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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d38eaba960b513bf08add2c454a5ccfad811966242f1fa006b77db6a15411ba' 
  AND token = 'DLGzdEr2BSv+Afk2dNPZjq/kWgWpA3Jrv0Mgsue02JQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}