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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5a92ca255248e0bf32fc142d6be60ff578b4bd4be5bbc5585d6e02d3963ecd' 
  AND token = '21RFwyy7zJtA44lL+xrrUiPbgeX5jjoLAy3ibmFDjHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}