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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f3a990449f0643c14cc0869d378418537bdaa38f105317845cfc83addd2d69' 
  AND token = '8eZGIwENyY0X7rY4uND3SQ4gCjbEs1ZCjOcuQqTo9+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}