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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caf12d48aa10bb43deb3537093c73e5069b6fb074d97100d07574a75f75a5180' 
  AND token = 'wwUvVrZ3V+iHwdE7nMUvneOYOPgBR5MQ9YMeidq3rL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}