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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '725ef33d7b83193224122827b799c9e2970b23ec54e250d3fb3df8eec29b4f55' 
  AND token = 'g7QPPppcm5XH5Hqql2A1WH2k4BS4ex/SoqJnBV3v8Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}