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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adbd23ac972d2ba4690a94c14a12ff0b9ee649a2dd02463b73c362da3293460d' 
  AND token = '60dRM0ZxdVAmsQgTPSVYOemsldC7qRLperAoS6KA8lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}