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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9853747370819525fca244e4f41a019c01a75813533a3483f08bb0afa6663d7e' 
  AND token = 'z5NjuGR556N0EwIGibKiuwhp6vj5NzSjTrpC1cH1kb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}