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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c4291f988472034be7381aa2bf6b31a37d4f8b375968606cbb0ffe8c3a1c8e' 
  AND token = 'M77ZAtHSo4YdJlh/KCEIFjk/WAUDEavbxosFiKPH+I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}