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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7624f955dfee241fa45e95e3833c1d7079e3c28efaa116f8643ad54b1f32b03' 
  AND token = 'giVIyvW/dTLg67CiB2j/LB0IM80nV8afJel4E6YhAhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}