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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d433a10318db03b747459d8e2e8e7e2c8dd25671cb98b67ec7bf6d0393c1316' 
  AND token = 'a7bqJRf6LO2KpAMNCs39myJja2Hqjgsl0Ci2x2FJ+MY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}