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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406c91e0d31e7b7e7a0a76d32f3401e4e1c6a1127d3f92a7c1f1c35176a08906' 
  AND token = 'qY4ZYsn9h1cqxffFGhm4WGcLxam+2Nkh4lmLdF8T0kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}