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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0977aad25b191a42a644ac1ae5d28d5ca928d2998b06795c8c855992d0776251' 
  AND token = '6IlEPeLtFVtthjpdNG+ugig/G5GC7usW4y5zBy3qJ2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}