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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bb6d6a4373cb66a2d2fd1411130c67aa45205dd8dbedafa5409df41f91c00f6' 
  AND token = 'DkqFim9kbniA0FUhhlSmIA1Y7trZ0htGYk8vTJaRTfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}