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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c0e9e2f3f9eb300365c1613e97f8de1d14505b75d368c8e4750cf3788e6e521' 
  AND token = 'wZmS9SIyvIdR9xRyp9KIMjePj1/+3yPRUg11TEI3phc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}