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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03f0b0b546e7513c4b307f4e5f6904e8321bb78440e24acb518ad6825158a113' 
  AND token = 'IrihXyKUrVRgRbVya1xpMulabyPfs9DcxPkiiUOQaCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}