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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d2ae1940b6e4678813f22087723ca2ad433e565df41cf7ca3f2f373b1ecc8ca' 
  AND token = 'kiiFJaSb+g3cUzJRMmoC9T3Z25FXF/MvA2e/4+4b8EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}