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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0fc4f6b7a186c9b659340151360dc8e89d4ad0995e1abc08716ea874ec78785' 
  AND token = 'qwdDiARrVbAQFtBK49X54rh+zIb8GnTHx7eJdKcDoO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}