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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5005d3da09509348fd25c9c6bc44e97966bb30b465aa64c6af5ad3dd3a6fd7f1' 
  AND token = 'jG93Y9x64yaY+9zayW3INxm6W9tN3GqCTfZLPE/sJMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}