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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe4c263878f6f9c2003e95c02fd49f677e7be8fdaee40d131614b0598629f9d9' 
  AND token = 'BANOqusQEPe2zTVQCUn2FOzOgpN7v1L8CelNpy/9lPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}