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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046bea17ea0f0282f1eb1768c7eb8eb492d5ec76a5ab04eb956625413a891f42' 
  AND token = 'PLmgHeg3r6mjbm5KUK9DELRHx6zn17WiBD+Q6XTaFTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}