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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b4d9878a32520d6e478aa3f7c4da8bb0b41d0f2f7017a5792d00520c810146' 
  AND token = 'Nroz0EjMNpCbV/iOSOkfUWsu/LvFgc1nY2UPKcJGt3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}