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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfd4f34036d202ee6366edd9fd9af461ea2e15601f0d40fb305ead43485307a2' 
  AND token = '07LRob/2ne+gkro+D02GMLS8TkHWRn29mZG+vhzAvW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}